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Systemic Anti-Cancer Therapies (SACT)

The content of this page is aimed at providing information and guidance on SACT to healthcare professionals. Information for patients can be found HERE.

Systemic Anti-Cancer Therapies (SACT) Clinical Group

SACT Clinical Lead: Dr Catherine Bale (Betsi Cadwaladr UHB)

SACT Nurse Lead: Dr Rosie Roberts (Velindre NHS Trust)

SACT Pharmacy Leads: Anthony Cadogan (Cwm Taf Morgannwg UHB), Tracy Parry (Betsi Cadwaladr UHB) and Gail Povey (Swansea Bay UHB)


The All Wales SACT Group meets three times a year and aims to provide a strategic lead for national SACT priorities, enabling a coordinated approach for developments such as e-prescribing, SACT datasets, coordination and monitoring of horizon scanning of cancer drugs and accessibility on a once for Wales basis.


For further information on the All Wales SACT Group, please contact

The Wales Cancer Network SACT and AOS Education Event was held virtually on the 11th and 12th May 2022.

Please CLICK HERE to view the full agenda. 

Recordings of the event are available via the links below:

Day 1 recording

Day 2 recording

For any queries please contact

National Institute for Health and Care Excellence (NICE)

NICE offers evidence-based guidelines and advice for practitioners in health, public health and social care.

For further information on NICE guidance for Cancer, please CLICK HERE.


National SACT Consent Forms

The All Wales SACT Group endorse the National SACT Consent Forms hosted on the CRUK Website.

The Wales representatives for the National Consent Form Steering Group are Dr Rosie Roberts (Velindre NHS Trust) and Simon Waters (Velindre NHS Trust).


UK Chemotherapy Board

The UK Chemotherapy Board has representation from the following National bodies:

  • The Association of Cancer Physicians (ACP)
  • The Royal College of Radiologists (RCR)
  • The Royal College of Physicians (RCP)
  • The Royal College of Pathologists (RCPath)
  • The UK Oncology Nursing Society (UKONS)
  • The British Oncology Pharmacy Association (BOPA)

The Wales representative for the UK Chemotherapy Board is Dr Catherine Bale (Betsi Cadwaladr UHB).

Current workstreams include:

  • Chemotherapy consent forms and related documents
  • Hepatitis B testing
  • Intrathecal Chemotherapy Standards
  • National SACT protocols
  • Standards for Reducing Risks Associated with Electronic Prescribing
  • Steroid prophylaxis for immunotherapy
  • National consensus on validity periods of blood tests and threshold values
  • Extravasation


All Wales SACT Authorisation & Prescribing Passport

The All Wales SACT Authorisation & Prescribing Passport is endorsed by the Wales Cancer Network. These competencies are designed to be used to allow all healthcare professionals to gain the appropriate skills, expertise and experience in the assessment, monitoring and prescribing of SACT in the area of their practice.

This passport is currently in use but is being reviewed and the updated version will be uploaded as soon as available.


UKONS SACT Administration Competency Passport

The UKONS SACT Administration Competency Passport is the agreed standard for administration of SACT.


Alert Cards

The All Wales Alert Cards have been developed for patients receiving chemotherapy and immunotherapy:

  • Chemotherapy Alert Card
  • Immunotherapy Alert Card
  • DPD and Chemotherapy Alert Card

For further information on how to order these cards, please contact


Patient Education Videos

Velindre Cancer Centre have developed education videos for patients and their families in both Welsh and English to provide information regarding the following key topics:


Sepsis and Cancer

Following positive patient feedback on these videos, members of the All Wales SACT Nurse Group are now working towards creating more education videos relevant to patients receiving SACT treatment across Wales.


Medicines Management Sub-Group

Previously known as the ePrescribing sub-group, the SACT Medicines Management Sub-Group was established by the All Wales SACT Group.

The group meets three times a year and aims to provide a multidisciplinary platform for making consensus recommendations relating to the best-practice use of SACT and SACT-supporting medicines, ensuring equity of access and optimisation of use. It also provides strategic leadership for medicines management priorities of the All Wales SACT Group.

This enables a coordinated approach for developments such as ePrescribing, SACT dataset, horizon scanning, governance and accessibility, and prioritising a Once-for-Wales approach, ensuring delivery against national standards agreed by the All Wales SACT Group.

The All Wales SACT Group collaborates with a range of national groups. Key groups include:

SACT Nurse Forum

The SACT Nurse Forum has been established to provide nurses from across Wales an opportunity to share best practice through collaboration and to collectively inform the development of practice and workforce standards. The forum is chaired by Dr Rosie Roberts (Velindre NHS Trust).


The Wales Cancer Network has set up the All Wales Genomics Oncology Group (AWGOG) to facilitate a multidisciplinary and coordinated national approach to the development and implementation of oncology-specific genomic services provided by the All Wales Medical Genomics Service (AWMGS).

For further information about Genomics and AWGOG, please CLICK HERE.


The All Wales AOS Group was established by the Wales Cancer Network and aims to provide a strategic lead for national acute oncology priorities and a forum for the ratification of All Wales developments enabling a coordinated approach, for example in the development of AOS datasets, pathways, documents and support tools in order to ensure a standardised, cohesive acute oncology service for Wales.

For further information about AOS and the All Wales AOS Group, please CLICK HERE.

All Wales Therapeutics and Toxicology Centre (AWTTC)

AWTTC is an NHS Wales organisation that works with patients, carers, patient organisations, healthcare professionals, the pharmaceutical industry, Welsh Government and other relevant UK organisations to recommend and ensure appropriate and effective use of medicines.

For further information about AWTTC, please CLICK HERE.